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Scientists are pursuing a number of theories including oxidative stress, glutamate toxicity, and mitochondrial dysfunction (Rowland 1994
While this seems counterintuitive (you might expect less side effects from weaker medication), degraded peptides with altered structures can sometimes trigger different inflammatory responses at the injection site
doi:10.1093/jnci/djv275 Irwin ML, McTiernan A, Baumgartner RN, et al
These different forms allow researchers to choose the most convenient method of administration based on preferences and requirements
Yellowing of the skin or the whites of the eyes (jaundice)
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