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Their antioxidant activity, mediated via Nrf2 pathway activation and upregulation of phase II detoxification enzymes (HO1, SOD, CAT), helps protect normal tissues from chemotherapyinduced oxidative damage
For example, microbiota-derived indole-3-propionic acid (IPA) is reduced in patients with IBD and can limit mucosal inflammation by promoting apoptosis of Th1/Th17 cells [255]
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Alongside monitoring your glutathione levels, maintaining a healthy lifestyle and diet is fundamental to bolster your bodys natural glutathione production
