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It is the most frequently reported side effect of tirzepatide, affecting roughly 15 to 30 percent of patients depending on the dose

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It is derived from the HGH amino acid sequence 176191 and was designed to retain the hormones fat-metabolising properties while avoiding its growth-promoting and blood sugaraltering effects (1)

Bryan, N.S., Petrosino, J.F

These side effects are typically very short-lived, if they occur at all, and should predictably resolve within 15 minutes of administration