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Studies demonstrate that Dihexa promotes dendritic spine formation, increases synaptic density, and enhances miniature excitatory postsynaptic currents (mEPSCs), indicating the formation of functional glutamatergic synapses
FIC, which is broadly recognized as the natural animal equivalent of IC/PBS in humans, demonstrates similar pathological characteristics
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Additionally, it was reported that trimetazidine (TMZ), a piperazine derivative, mediated activation of the GSH system and had antioxidant and cytoprotective effects in several myocardial injury models [210,211,212,213]
The critical gap: There are no published human clinical trials examining BPC-157 for depression, anxiety, or any psychiatric condition
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