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This article summarizes what research shows in specific clinical trial populations and what patterns may be worth tracking, not whether stopping is the right decision for you

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GLP-1s can sometimes cause a slight increase in resting heart rate

Interestingly, sigma-1 (Sig1R) agonists, such as BD1047, were shown to downregulate CatB, ameliorating HAND, especially in cocaine users (Lpez et al., 2019)

Many athletes take it 30-60 minutes before training as part of their pre-workout routine

Expected weight loss with the -enatides is only around 34 pounds, which is far less than with -glutides