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Indeed, recent mechanistic studies highlight the intricate crosstalk between Myc and p53, where Myc overexpression induces p53-dependent apoptosis, and as a consequence, Myc-associated tumors often require disruption of the apoptosis pathway to promote cell proliferation, thereby conferring an evolutionary advantage to TP53 loss 123
Gut-Brain Axis Gastroprotection Gastrointestinal Protection & Neuroprotection Protection of the gastric and intestinal mucosa: ulcers, colitis, NSAID lesions
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A 12-year randomized clinical study involving epithalamin found that this peptide was associated with a geroprotective effect and increased the lifespan in elderly subjects with heart disease and accelerated aging of the cardiovascular system [11]
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