Because it also can't be blocked, you can combine it with effects that trigger when you deal combat damage without worry
Remove key creatures like Merfolk Mistbinder, Deeproot Elite and Kumena, Tyrant of Orazca or creatures with auras (Curious Obsession and One with the Wind)
The most expensive Mega Evolution Base Set cards are the Mega Lucario ex Mega Hyper Rare and Mega Gardevoir ex Mega Hyper Rare both among the rarest pulls in the set
The two pairs of rare Meld cards, given how powerful they are on their own, will also be worth trying, with Gisela in particular having a similar set of hyper-efficient stats to the much loved (and hated) Baneslayer Angel from the Standard of the past
Big beaters like Tarmogoyf had it too good for too long, all hail the 2/2s and below
Wizards is trying to tell you that you have no excuse not to run more interaction